I think there are a couple of places to rent.
More infohttp://maps.google.com/maps/place?oe=UTF-8&gfns=1&um=1&ie=UTF-8&q=car+rentals+port+clinton+oh&fb=1&gl=us&hq=car+rentals&hnear=Port+Clinton,+OH&cid=9834444374667940094